Selected Publications

Excitation wavelength-dependent EPR study on the influence of the conformation of multiporphyrin arrays on triplet state delocalization.

Tait CE, Neuhaus P, Peeks MD, Anderson HL, Timmel CR.Physical chemistry chemical physics, 18(7), 5275-5280 (2016)
10.1039/c5cp07424j

Exploiting orientation-selective DEER: determining molecular structure in systems containing Cu(ii) centres.

Bowen AM, Jones MW, Lovett JE, Gaule TG, McPherson MJ, Dilworth JR, Timmel CR, Harmer JR. Physical chemistry chemical physics, 18(8), 5981-5994 (2016).
10.1039/c5cp06096f

Chemical amplification of magnetic field effects relevant to avian magnetoreception.

Kattnig DR, Evans EW, Djean V, Dodson CA, Wallace MI, Mackenzie SR, Timmel CR, Hore PJ. Nature chemistry, 8(4), 384-391 (2016).
10.1038/nchem.2447

Spectroscopic and Crystal Field Consequences of Fluoride Binding by [Yb-DTMA](3+) in Aqueous Solution.

Blackburn OA, Chilton NF, Keller K, Tait CE, Myers WK, McInnes EJ, Kenwright AM, Beer PD, Timmel CR, Faulkner S.Angewandte Chemie (International ed. in English), 54(37), 10783-10786 (2015).
10.1002/anie.201503421

Sensitive fluorescence-based detection of magnetic field effects in photoreactions of flavins.

Evans EW, Li J, Storey JG, Maeda K, Henbest KB, Dodson CA, Hore PJ, Mackenzie SR, Timmel CR.Physical chemistry chemical physics, 17(28), 18456-18463 (2015).
10.1039/c5cp00723b

Transient EPR Reveals Triplet State Delocalization in a Series of Cyclic and Linear p-Conjugated Porphyrin Oligomers.

Tait CE, Neuhaus P, Peeks MD, Anderson HL, Timmel CR.Journal of the American Chemical Society, 137(25), 8284-8293 (2015).
10.1021/jacs.5b04511

Triplet state delocalization in a conjugated porphyrin dimer probed by transient electron paramagnetic resonance techniques.

Tait CE, Neuhaus P, Anderson HL, Timmel CRJournal of the American Chemical Society, 137(20), 6670-6679 (2015).
10.1021/jacs.5b03249

HYSCORE on Photoexcited Triplet States

Tait CE, Neuhaus P, Anderson HL, Timmel CR, Carbonera D, Di Valentin M.APPLIED MAGNETIC RESONANCE, 46(4), 389-409 (2015).
10.1007/s00723-014-0624-5

Probing a chemical compass: novel variants of low-frequency reaction yield detected magnetic resonance.

Maeda K, Storey JG, Liddell PA, Gust D, Hore PJ, Wedge CJ, Timmel CR.Physical chemistry chemical physics, 17(5), 3550-3559 (2015).
10.1039/c4cp04095c

Crystal structure of the Bacillus subtilis phosphodiesterase PhoD reveals an iron and calcium-containing active site.

Rodriguez F, Lillington J, Johnson S, Timmel CR, Lea SM, Berks BC.The Journal of biological chemistry, 289(45), 30889-30899 (2014).
10.1074/jbc.M114.604892

Broadband cavity-enhanced detection of magnetic field effects in chemical models of a cryptochrome magnetoreceptor.

Neil SR, Li J, Sheppard DM, Storey J, Maeda K, Henbest KB, Hore PJ, Timmel CR, Mackenzie SR.The journal of physical chemistry. B, 118(15), 4177-4184 (2014).
10.1021/jp500732u

Orientation-Selective DEER Using Rigid Spin Labels, Cofactors, Metals, and Clusters

Bowen AM, Tait CE, Timmel CR, Harmer JR.STRUCTURAL INFORMATION FROM SPIN-LABELS AND INTRINSIC PARAMAGNETIC CENTRES IN THE BIOSCIENCES, 152, 283-327) (2014).
10.1007/430_2013_115

Structural Information from Spin-Labels and Intrinsic Paramagnetic Centres in the Biosciences

Timmel CR, Harmer JR.STRUCTURAL INFORMATION FROM SPIN-LABELS AND INTRINSIC PARAMAGNETIC CENTRES IN THE BIOSCIENCES, 152, V-VII (2014).

Magnetic field effects in flavoproteins and related systems

Evans EW, Dodson CA, Maeda K, Biskup T, Wedge CJ, Timmel CR. Interface Focus, 3(5 (2013).
10.1098/rsfs.2013.0037

Investigating the structure of the factor B vWF-A domain/CD55 protein-protein complex using DEER spectroscopy: Successes and pitfalls

Lovett JE, Abbott RJM, Roversi P, Johnson S, Caesar JJE, Doria M, Jeschke G, Timmel CR, Lea SM. Molecular Physics, 111(18-19), 2865-2872 (2013).
10.1080/00268976.2013.827754

Spin-locking in low-frequency reaction yield detected magnetic resonance.

Wedge CJ, Lau JC, Ferguson KA, Norman SA, Hore PJ, Timmel CR. Phys Chem Chem Phys, 15(38), 16043-16053 (2013).
10.1039/c3cp52019f

Structural model for the protein-translocating element of the twin-arginine transport system.

Rodriguez F, Rouse SL, Tait CE, Harmer J, De Riso A, Timmel CR, Sansom MS, Berks BC, Schnell JR.Proc Natl Acad Sci U S A , 110(12), E1092-E1101 (2013).
10.1073/pnas.1219486110

Magnetically sensitive light-induced reactions in cryptochrome are consistent with its proposed role as a magnetoreceptor

Kiminori Maeda, Alexander J. Robinson, Kevin B. Henbest, Hannah J. Hogben, Till Biskup, Margaret Ahmad, Erik Schleicher, Stefan Weber, Christiane R. Timmel and Peter J. Hore, Proc. Natl. Acad. Sci. USA, 109(13), 4774-4779 (2012).
DOI: 10.1073/pnas.1118959109

Characterisation of the paramagnetic [2Fe-2S](+) centre in palustrisredoxin-B (PuxB) from Rhodopseudomonas palustris CGA009: g-matrix determination and spin coupling analysis

Joseph A.B. Abdalla, Alice M. Bowen, Stephen G. Bell, Luet L. Wong, Christiane R. Timmel and Jeffrey Harmer, Phys. Chem. Chem. Phys., 14(18), 6526-6537 (2012).
DOI: 10.1039/c2cp24112a

Following Radical Pair Reactions in Solution: A Step Change in Sensitivity Using Cavity Ring-Down Detection

Kiminori Maeda, Simon R.T. Neil, Kevin B. Henbest, Stefan Weber, Erik Schleicher, Peter J. Hore, Stuart R. Mackenzie and Christiane R. Timmel, J. Am. Chem. Soc, 133(44), 17807-17815 (2011).
DOI: 10.1021/ja206783t

The Short-Lived Signaling State of the Photoactive Yellow Protein Photoreceptor Revealed by Combined Structural Probes

Pradeep L. Ramachandran, Janet E. Lovett, Patrick J. Carl, Marco Cammarata, Jae Hyuk Lee, Yang Ouk Jung, Hyotcherl Ihee, Christiane R. Timmel and Jasper J. van Thor, J. Am. Chem. Soc., 133(24), 9395-9404 (2011).
DOI: 10.1021/ja200617t

Shigella flexneri Spa15 Crystal Structure Verified in Solution by Double Electron Electron Resonance

James E.D. Lillington, Janet E. Lovett, Steven Johnson, Pietro Roversi, Christiane R. Timmel and Susan M. Lea, J. Mol. Biol., 405(2), 427-435 (2011).
DOI: 10.1016/j.jmb.2010.10.053

Spin selective recombination kinetics of a model chemical magnetoreceptor

Kiminori Maeda, Christopher J. Wedge, Jonathan G. Storey, Kevin B. Henbest, Paul A. Liddell, Gerdenis Kodis, Devens Gust, P. J. Hore and Christiane R. Timmel, Chem. Commun., 47(23), 6563-6565 (2011).
DOI: 10.1039/c1cc11625h

Shigella flexneri Spa15 Crystal Structure Verified in Solution by Double Electron Electron Resonance

James E.D. Lillington, Janet E. Lovett, Steven Johnson, Pietro Roversi, Christiane R. Timmel and Susan M. Lea, J Mol. Bio., 405(2), 427-435 (2011).
DOI: 10.1016/j.jmb.2010.10.053

Cavity enhanced detection methods for probing the dynamics of spin correlated radical pairs in solution

Simon R.T. Neil, Kiminori Maeda, Kevin B. Henbest, Martin Goez, Robert Hemmens, Christiane R. Timmel and Stuart R. Mackenzie, Mol. Phys., 108(7-9), 993-1003 (2010).
DOI: 10.1080/00268971003614368

Protein Surface Interactions Probed by Magnetic Field Effects on Chemical Reactions

Kiminori Maeda, Alexander J. Robinson, Kevin B. Henbest, Emma J. Dell and Christiane R. Timmel, J. Am. Chem. Soc., 132(5), 1466-1467 (2010).
DOI: 10.1021/ja908988u
Read the feature in C&E News

Possible involvement of superoxide and dioxygen with cryptochrome in avian magnetoreception: Origin of Zeeman resonances observed by in vivo EPR spectroscopy

Hannah J. Hogben, Olga Efimova, Nicola Wagner-Rundell, Christiane R. Timmel and P. J. Hore, Chem. Phys. Lett., 480(1-3), 118-122 (2009).
DOI: 10.1016/j.cplett.2009.08.051

Probing Flexibility in Porphyrin-Based Molecular Wires using Double Electron Electron Resonance

Janet E. Lovett, Markus Hoffmann, Arjen Cnossen, Alexander T. J. Shutter, Hannah J. Hogben, John E. Warren, Sofia I. Pascu, Christopher W. M. Kay, Christiane R. Timmel and Harry L. Anderson, J. Am. Chem. Soc., 131(38), 13852-13859 (2009).
DOI: 10.1021/ja905796z

Effect of magnetic fields on cryptochrome-dependent responses in Arabidopsis thaliana

Sue-Re Harris, Kevin B.  Henbest, Kiminori Maeda, John R. Pannell, Christiane R. Timmel, P. J. Hore and Haruko Okamoto, J. R. Soc. Interface, 6(41), 1193-1205 (2009).
DOI: 10.1098/rsif.2008.0519

Structural Information from Orientationally Selective DEER Spectroscopy

J. E. Lovett, A. M. Bowen, C. R. Timmel, M. W. Jones, J. R. Dilworth, D. Caprotti, S. G. Bell, L. L. Wong and J. Harmer, Phys. Chem. Chem. Phys., 11(31), 6840-6848 (2009).
DOI: 10.1039/b907010a

Radiofrequency Polarization Effects in Low-Field Electron Paramagnetic Resonance

C. J. Wedge, Christopher T. Rodgers, Stuart A. Norman, Neville Baker, Kiminori Maeda, Kevin B. Henbest, P. Styles, P. J. Hore and C. R. Timmel, Phys. Chem. Chem. Phys., 11(31), 6573-6579 (2009).
DOI: 10.1039/b907915g

Radiofrequency Polarization Effects in Zero-Field Electron Paramagnetic Resonance

Christopher T. Rodgers, C. J. Wedge, Stuart A. Norman, Philipp Kukura, Karen Nelson, Neville Baker, Kiminori Maeda, Kevin B. Henbest, P. J. Hore and C. R. Timmel, Phys. Chem. Chem. Phys., 11(31), 6569-6572 (2009).
DOI: 10.1039/b906102a

Magnetic Compass of Birds Is Based on a Molecule with Optimal Directional Sensitivity

Thorsten Ritz, Roswitha Wiltschko, P. J. Hore, Christopher T. Rodgers, Katrin Stapput, Peter Thalau, Christiane R. Timmel and Wolfgang Wiltschko, Biophys. J., 96(8), 3451-3457 (2009).
DOI: 10.1016/j.bpj.2008.11.072

Quenching Mechanisms and Diffusional Pathways in Micellar Systems Unravelled by Time-Resolved Magnetic-Field Effects

Martin Goez, Kevin B. Henbest, Emma G. Windham, Kiminori Maeda and C. R. Timmel, Chem. Eur. J., 15(24), 6058-6064 (2009).
DOI: 10.1002/chem.200802502

M. Britton and C. R. Timmel in Magnetic Resonance Microscopy: Spatially Resolved NMR Techniques and Applications, edited by S. L. Codd and J. D. Seymour
Wiley-VCH Weinheim 2009
ISBN: 978-3-527-32008-0

SQUID Magnetometry as a Tool for Following a Clock Reaction in Solution

R. Evans, K. B  Henbest, M. A. Hayward, M. M. Britton, K. Maeda and C. R. Timmel, Dalton Trans., (14), 2467 (2009).
DOI: 10.1039/b819977a

Magnetic Field Effect on the Photoactivation Reaction of Escherichia coli DNA photolyase

K. B.  Henbest, K. Maeda, P. J. Hore, M. Joshi, A. Bacher, R. Bittl, S. Weber, C. R. Timmel and E. Schleicher, PNAS, 105(38), 14395-14399 (2008).
DOI: 10.1073/pnas.0803620105

Chemical Compass Model of Avian Magnetoreception

K. Maeda, K. B  Henbest, F. Cintolesi, I. Kuprov, C. T. Rodgers, P. A. Liddell, D. Gust, C. R. Timmel and P. J. Hore, Nature, 453(7193), 387 (2008).
DOI: 10.1038/nature06834
DOI: 10.1038/news.2008.788 (Nature News)

Chemical magnetoreception: bird cryptochrome 1a is excited by blue light and forms long-lived radical-pairs

M. Liedvogel, K. Maeda, K. Henbest, E. Schleicher, T. Simon, C.R. Timmel, P.J. Hore and H. Mouritsen, PLoS ONE, 2(10), e1106 (2007).
DOI: 10.1371/journal.pone.0001106

Evidence from EPR that nitroxide spin labels attached to human hemoglobin alter their conformation upon freezing

J. E. Banham, G. Jeschke and C. R. Timmel, Mol. Phys., 105(15-16), 2041 (2007).
DOI: 10.1080/00268970701579501

Distance Measurements in the Borderline Region of Applicability of CW EPR and DEER: A Model Study on a Homologous Series of Spin-Labelled Peptides

J. E. Banham, C. M. Baker, S. Ceola, I. J. Day, G. H. Grant, E. J. J. Groenen, C. T. Rodgers, G. Jeschke and C. R. Timmel, J. Mag. Res., 191(2), 202-218 (2008).
DOI: 10.1016/j.jmr.2007.11.023

Determination of radical re-encounter probability distributions from magnetic field effects on reaction yields

C. T. Rodgers, S. A. Norman, K. B. Henbest, C. R. Timmel and P. J. Hore, J. Am. Chem. Soc., 129 (21), 6746–6755 (2007).
DOI: 10.1021/ja068209l

DeerAnalysis2006 - A Comprehensive Software Package for Analyzing Pulsed ELDOR Data

G. Jeschke, V. Chechik, P. Ionita, A. Godt, H. Zimmermann, J. Banham, C. R. Timmel, D. Hilger and H. Jung, Appl. Magn. Reson., 30(3-4), 473-498 (2006).
DOI: 10.1007/BF03166213

Magnetic Resonance Imaging of the Manipulation of a Chemical Wave Using an Inhomogeneous Magnetic Field

R. Evans, C. R. Timmel, P. J. Hore and M. M. Britton, J. Am. Chem. Soc., 128(22), 7309-7314 (2006).
DOI: 10.1021/ja0608287

The Characterization of Weak Protein-Protein Interactions: Evidence from DEER for the Trimerization of a von Willebrand Factor A Domain in Solution

J. E. Banham, C. R. Timmel, R. J. M. Abbott, S. M. Lea and G. Jeschke, Angew. Chem., Int. Ed., 45(7), 1058-1061 (2006).
DOI: 10.1002/anie.200503720

Photoionization of TMPD in DMSO solution: mechanism and magnetic field effects

K.B. Henbest, E. Athanassiades, K. Maeda, I. Kuprov, P. J. Hore and C.R. Timmel, Mol. Phys., 104(10-11), 1789-1794 (2006).
DOI: 10.1080/00268970600611017

Measurement of magnetic field effects on radical recombination reactions using triplet-triplet energy transfer

K.B. Henbest, K. Maeda, E. Athanassiades, P.J. Hore and C.R. Timmel, Chem. Phys. Lett., 421(4-6), 571-576 (2006).
DOI: 10.1016/j.cplett.2006.01.106

Low-Field Optically Detected EPR Spectroscopy of Transient Photoinduced Radical Pairs

C. T. Rodgers, K. B. Henbest, P. Kukura, C. R. Timmel and P. J. Hore, J. Phys. Chem. A, 109(23), 5035-5041 (2005).
DOI: 10.1021/jp050765z

Influence of Dipolar Interactions on Radical Pair Recombination Reactions Subject to Weak Magnetic Fields

A. R. O'Dea, A. F. Curtis, N. J. B. Green, C. R. Timmel and P. J. Hore, J. Phys. Chem. A, 109(5), 869-873 (2005).
DOI: 10.1021/jp0456943

Magnetic field effect on singlet oxygen production in a biochemical system

Y. Liu, R. Edge, K. B. Henbest, C. R. Timmel, P. J. Hore and P. Gast, Chem. Comm., (2), 174-176 (2005).
DOI: 10.1039/b413489c

Magnetic Resonance Imaging Study of a Magnetic Field Dependent Chemical Wave

R. Evans, C. R. Timmel, P. J. Hore and M. M. Britton, Chem. Phys. Lett., 397(1-3), 67-72 (11-1).
DOI: 10.1016/j.cplett.2004.08.079

A Study of Spin Chemistry in Weak Magnetic Fields

C. R. Timmel and K. B. Henbest, Phil. Trans. R. Soc. Lond. A, 362(1825), 2573-2589 (2004).
DOI: 10.1098/rsta.2004.1459

Radio Frequency Magnetic Field Effects on a Radical Recombination Reaction: A Diagnostic Test for the Radical Pair Mechanism

K. B. Henbest, P. Kukura, C. T. Rodgers, P. J. Hore and C. R. Timmel, J. Am. Chem. Soc., 126(26), 8102-8103 (2004).
DOI: 10.1021/ja048220q

Anisotropic recombination of an immobilized photoinduced radical pair in a 50-µT magnetic field: a model avian photomagnetoreceptor

F. Cintolesi, T. Ritz, C. W. M. Kay, C. R. Timmel and P. J. Hore, Chem. Phys., 294(3), 385-399 (2003).
DOI: 10.1016/S0301-0104(03)00320-3

Low field RYDMR: effects of orthogonal static and oscillating magnetic fields on radical recombination reactions

J. R. Woodward, C. R. Timmel, P. J. Hore and K. A. McLauchlan, Mol. Phys., 100(8), 1181-1186 (2006).
DOI: 10.1080/00268970110109961

Oscillating magnetic field effects on chemical reaction yields

J. R. Woodward, C. R. Timmel, P.J. Hore and K. A. McLauchlan, RIKEN Review, (44), 79-81 (2002).

Radiofrequency magnetic field effects on electron-hole recombination

J. R. Woodward, C. R. Timmel, K. A. McLauchlan and P. J. Hore, Phys. Rev. Lett., 87(7), 077602 (2001).
DOI: 10.1103/PhysRevLett.87.077602

A zero-field electron spin resonance spectrometer for the study of transient radical ion pairs

C. R. Timmel, J. R. Woodward, K. A. McLauchlan, P. J. Hore and D. V. Stass, Meas. Sci. Technol., 12(5), 635-643 (2001).
DOI: 10.1088/0957-0233/12/5/311

Model calculations of magnetic field effects on the recombination reactions of radicals with anisotropic hyperfine interactions

C. R. Timmel, F. Cintolesi, B. Brocklehurst and P. J. Hore, Chem. Phys. Lett., 334(4-6), 387-395 (2001).
DOI: 10.1016/S0009-2614(00)01436-6

The effects of weak magnetic fields on radical recombination reactions in micelles

R. W. Eveson, C. R. Timmel, B. Brocklehurst, P. J. Hore and K. A. McLauchlan, Int. J. Radiat. Biology, 76(11), 1509-1522 (2000).
DOI: 10.1080/09553000050176270

Radiofrequency magnetic field effects on chemical reaction yields

D. V. Stass, J. R. Woodward, C. R. Timmel, K. A. McLauchlan and P. J. Hore, Chem. Phys. Lett., 329(1-2), 15-22 (2000).
DOI: 10.1016/S0009-2614(00)00980-5

Effects of weak magnetic fields on free radical recombination reactions

C. R. Timmel, U. Till, B. Brocklehurst, K. A. McLauchlan and P. J. Hore, Mol. Phys., 95(1), 71-89 (1998).
DOI: 10.1080/00268979809483134

The influence of very small magnetic fields on radical recombination reactions in the limit of slow recombination

U. Till, C. R. Timmel, B. Brocklehurst and P. J. Hore, Chem. Phys. Lett., 298(1-3), 7-14 (1998).
DOI: 10.1016/S0009-2614(98)01158-0

Spin-correlated radical pairs: microwave pulse effects on lifetimes, electron spin echo envelope modulations, and optimum conditions for detection by electron spin echo spectroscopy

C. R. Timmel, C. E. Fursman, A. J. Hoff and P. J. Hore, Chem. Phys., 226(3), 271-283 (1998).
DOI: 10.1016/S0301-0104(97)00283-8

The nuts and bolts of distance determination and zero- and double-quantum coherence in photoinduced radical pairs

A. J. Hoff, P. J. Gast, S. A. Dzuba, C. R. Timmel, C. E. Fursman and P. J. Hore, Spectrochimica Acta, 54(14), 2283-2293 (1998).
DOI: 10.1016/S1386-1425(98)00211-X

Resonant radiofrequency magnetic field effects on a chemical reaction

J. R. Woodward, R. J. Jackson, K. A. McLauchlan, C. R. Timmel and P. J. Hore, Chem. Phys. Lett., 272(5-6), 376-382 (1997).
DOI: 10.1016/S0009-2614(97)00542-3

Oscillating magnetic field effects on the yields of radical pair reactions

C. R. Timmel and P. J. Hore, Chem. Phys. Lett., 257(3-4), 401-408 (1996).
DOI: 10.1016/0009-2614(96)00466-6

Flip-angle effects in Fourier transform EPR spectra of spin-correlated radical pairs

C. R. Timmel and P. J. Hore, Chem. Phys. Lett., 226(1-2), 144-150 (1994).
DOI: 10.1016/0009-2614(94)00695-4